Canadian Health Measures Survey (CHMS). Content summary for cycles 1 to 6 (2018)

Introduction

A blank shaded cell in the table indicates that the questionnaire topic, measure or lab test listed under the subject column is not included in the corresponding collection cycle. In the tables, the cell indicates the age ranges for which the questionnaire topic, measure or lab test is applicable.

When combining or comparing data between cycles, see the most recent instruction document for combining CHMS data, as well as the Data Dictionary and User Guide for information and relevant procedures.

Type Legend

  • PM Physical Measure
  • Q Questionnaire
  • S Sample
  • SC Specimen Collection

Matrix Legend

  • B Blood
  • U Urine
  • S Saliva
  • H Hair
  • IAS Indoor Air Sampler
  • TWS Tap Water Sampler
Table 1: Household Questionnaire and Sample Collection
Theme Module Type Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 2014-2015 Cycle 5 2016-2017 Cycle 6 2018-2019
Age (years)
Alcohol Alcohol use Q 12-79 12-79 12-79 12-79 12-79 12-79
Anthropometry Height and weight (self report) Q 6-79 3-79 3-79 3-79 3-79 3-79
Weight change Q 18-79 18-79          
Chronic conditions Chronic conditions Q 6-79 3-79 3-79 3-79 3-79 3-79
PhlegmFootnote 10 Q 6-79 3-79 3-79 3-79      
Drug/Medication use Illicit drug use Q 14-79 14-79 14-79 14-79 14-79 14-79
Medication useFootnote 1 Q 6-79 3-79 3-79 3-79 3-79 3-79 1-79
Environmental exposure Grooming product useFootnote 2 Q 6-79          
Hobbies Q 6-79 3-79 3-79 3-79      
Housing characteristicsFootnote 3 Q 6-79 3-79         1-79
Tap water collectionFootnote 8 S     Data at Household Level     Data HHLD Level
Family medical history Family medical history Q 6-79 3-79 3-79 3-79    
General health General health Q 6-79 3-79 3-79 3-79 3-79 3-79
Health utility index Q 6-79 6-79     6-79 6-79  
Strengths and difficultiesFootnote 4 Q 6-17 6-17 4-17 4-17     4-17
Infection markers Hepatitis Q 6-79 3-79 3-79 3-79    
Human papillomavirus vaccine Q   9-39  9-59         
Toxoplasmosis Q         3-79    
Musculoskeletal health Bone health- Medication Q         3-79 3-79
Bone health- Menopause Q         40-65 (F) 40-65 (F) 40-65 (F)
Fracture history Q         3-79 3-79 1-79
Nutrition Dietary fat consumption Q 6-79 3-79 3-79 3-79 3-79 3-79
Grains, fruits and vegetables consumption Q 6-79 3-79 3-79 3-79 3-79 3-79 3-79
Meat and fish consumptionFootnote 5 Q 6-79            
Meat consumptionFootnote 5 Q   3-79 3-79 3-79 3-79 3-79 3-79
Milk & Dairy consumption Q 6-79 3-79 3-79 3-79 3-79 3-79 3-79
Salt consumption Q 6-79 3-79 3-79 3-79 3-79 3-79 3-79
Water & soft drink consumption Q 6-79 3-79 3-79 3-79 3-79 3-79 3-79
Oral health Oral health  Q 6-79          
Physical activity Children's physical activity Q 6-11 3-11 3-11 3-11 3-11 3-11
International physical activityFootnote 6 Q     12-79        
Physical activities (PAC)Footnote 7 Q 12-79 12-79          
Physical Activities for Youth  Q       12-17 12-17 12-17 12-17
Physical Activities-Adults Q       18-79 18-79 18-79 18-79
Sedentary activities Q 12-79 12-79 12-79 12-79 12-79 12-79 3-79
Time spent outdoors Q     3-14 3-14 3-79 3-79  
Neighbourhood environment Q         3-79 3-79  
Pregnancy/Birth Birth Control Q         12-79 12-79
Birth information Q 6-11 3-11 3-11 3-11 3-11 3-11 1-11
Breastfeeding Q 14-79 14-79         14-79
Breastfeeding information Q 6-11 3-11 3-11 3-11 3-11 3-11 1-11
Maternal breastfeeding Q 14-79 14-79     14-79 14-79 14-79
Pregnancy Q 14-59 14-59 14-59 14-59 14-59 14-59 14-59
Pregnancy information Q 6-11 3-11 3-11 3-11 3-11 3-11 1-11
Sexual health Pap smear test Q   14-79 14-79      
Sexual behaviour Q 14-79 14-79 14-79 14-79 14-79 14-79 14-79
Sleep Sleep apnea Q         18-79 18-79
Sleep Q 6-79 3-79 3-79 3-79     3-79
Smoking Electronic Cigarette Q         12-79 12-79
Exposure to second-hand smoke Q 6-79 3-79 3-79 3-79 3-79 3-79 1-79
Exposure to second-hand vapor Q         3-79 3-79 1-79
Smoking Q 12-79 12-79 12-79 12-79 12-79 12-79 12-79
Socio-demographic characteristics Education Q 15-79 15-79 12-79 3-79 3-79 3-79
Income Q 6-79 3-79 3-79 3-79 3-79 3-79 1-79
Labour force activity Q 15-75 15-75 15-75 15-75 15-75 15-75 15-75
Socio-demographic characteristics Q 6-79 3-79 3-79 3-79 3-79 3-79 1-79
Language Extended Q     3-79 3-79 3-79 3-79 1-79
Vision Vision Household Q         3-79 3-79
Vision PrescriptionFootnote 9 Q         6-79    
Vitamin D Sun Exposure Q 6-79 3-79        

(F) = Females

Footnote 1

Data from the Medication use questions at the household visit is combined with data from the medication use questions at the mobile examination centre (MEC) visit to form a medications data file.

Return to footnote 1 referrer

Footnote 2

Questionnaire administered during the mobile examination centre visit for cycle 2.

Return to footnote 2 referrer

Footnote 3

Portions of the questionnaire administered during the mobile examination centre visit in cycles 3 and 4.

Return to footnote 3 referrer

Footnote 4

Strengths and difficulties questionnaire - Robert Goodman.

Return to footnote 4 referrer

Footnote 5

Fish portion of meat and fish consumption questionnaire modified and administered during the mobile examination centre visit starting at Cycle 2.

Return to footnote 5 referrer

Footnote 6

International Physical Activity Questionnaire (IPAQ).

Return to footnote 6 referrer

Footnote 7

As of cycle 4, physical activity is divided into two blocks: one for youth (12 to 17); and one for adults (18 to 79).

Return to footnote 7 referrer

Footnote 8

A wide variety of lab tests are done on the specimen. A questionnaire to gather more information for the water analysis is administered at the mobile examination center.

Return to footnote 8 referrer

Footnote 9

Will be collected at the mobile examination centre only in Cycle 6

Return to footnote 9 referrer

Footnote 10

Phlegm is no longer collected in Cycle 7 and 8 as spirometry has been delayed to Cycle 9

Return to footnote 10 referrer

Table 2: Mobile Examination Centre (MEC) Questionnaires, Physical Measures, Sample and Specimen Collection
Theme Subject Type Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 2014-2015 Cycle 5 2016-2017 Cycle 6 2018-2019
Age (years)
Anthropometry Standing height PM 6-79 3-79 3-79 3-79 3-79 3-79
Recumbent length PM             1
Sitting height PM 6-79 3-79 3-79 3-79     3-79
Weight PM 6-79 3-79 3-79 3-79 3-79 3-79 1-79
Skinfolds PM 6-79 3-79          
Waist circumferenceFootnote 1 PM 6-79 3-79 3-79 3-79 3-79 3-79 3-79
Hip circumference PM 6-79 3-79 3-79 3-79      
Neck circumference PM   3-19     3-79 3-79  
Cardiovascular health and fitness Blood pressure (resting) PM 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11,Footnote 12
Heart rate (resting) PM 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11 6-79Footnote 11, Footnote 12 6-79Footnote 13
Modified Canadian Aerobic Fitness Test (mCAFT step test) PM 6-69 8-69     8-69 8-69  
Drug/Medication use Medication useFootnote 2 Q 6-79 3-79 3-79 3-79 3-79 3-79
Environmental exposure  Grooming product useFootnote 3 Q   3-79        
Indoor air Questions + SamplerFootnote 4 Q + S   Data at Household Level      
Water Analysis QuestionsFootnote 5 Q     Data at Household Level     Data at Household Level
Hearing Hearing ability Q     3-79 3-79    
Noise exposure Q     3-79 3-79      
Otoscopy PM     3-79 3-79      
Tympanometry PM     3-79 3-79      
Otoacoustic Emissions PM     3-79 3-79      
Audiometry PM     6-79 6-79      
Lung health Fractional Exhaled Nitric Oxide PM     6-79      
Spirometry PM 6-79 6-79 6-79 6-79      
Musculoskeletal fitness Hand grip strength PM 6-79 6-79 6-79 6-79 6-79 6-79
Partial curl-ups PM 6-69 8-69          
Sit and reach PM 6-69 6-69     6-69 6-69  
Musculoskeletal health Peripheral quantitative computed tomography (pQCT) PM         6-79 6-79
Mechanography
(multiple 2 legged hopping)
PM         6-79 6-79 6-79Footnote 17
Mechanography
(single 2 legged jump)
PM         6-79 6-79 6-79Footnote 17
Dual-energy x-ray absorptiometry (DXA) PM             1-79
Nutrition  Fish and shellfish consumption Q   3-79  3-79 3-79 3-79 3-79
Seaweed Consumption Q             1-79
Recent Consumption (48h)               1-79
Oral health Oral health examination PM 6-79          
Physical activity Accelerometry (activity monitor)Footnote 6 PM 6-79Footnote 14 3-79Footnote 14 3-79Footnote 14 3-79Footnote 14 3-79Footnote 14 3-79Footnote 14
Specimen collectionFootnote 7,Footnote 8 Blood collection SC 6-79 3-79 3-79 3-79 3-79 3-79
Urine collection SC 6-79 3-79 3-79 3-79 3-79 3-79 3-79
Home urine collectionFootnote 9 SC         3-79 3-79 3-79
Saliva Collection SC         3-79   1-79
Hair Sampling SC         20-59    
Vision  Vision Questions Q         3-79 3-79
Visual acuity PM         6-19,(20-39)Footnote 10, 40-79 6-19,(20-39)Footnote 10, 40-79  
Visual fieldFootnote 16 PM         (20-39)Footnote 10, 40-79 (20-39)Footnote 10, 40-79  
Retinal photographyFootnote 16 PM         (20-39)Footnote 10, 40-79 (20-39)Footnote 10,40-79  
Intraocular pressure PM         (20-39)Footnote 10, 40-79 (20-39)Footnote 10, 40-79  
Vitamin D Skin pigmentation PM     3-79 3-79    
Sun Exposure Q     3-79 3-79     3-79
Footnote 1

Cycle 1 used World Health Organization (WHO), Cycle 2 used both the WHO and National Institute of Health (NIH) measurement protocols (correction factor was published), Cycle 3+ NIH protocol only.

Return to footnote 1 referrer

Footnote 2

Data from the medication use questions at the household visit is combined with data from the medication use questions at the mobile examination centre visit to form a medications data file.

Return to footnote 2 referrer

Footnote 3

Questions administered during the household questionnaire in cycle 1.

Return to footnote 3 referrer

Footnote 4

Instructions provided to respondents on how to set up the indoor air monitor in their household for seven days directly following their visit to the mobile examination centre.

Return to footnote 4 referrer

Footnote 5

Questionnaire to gather more information for the water analysis of the sample that is collected at the household.

Return to footnote 5 referrer

Footnote 6

Instructions provided to respondents to wear an activity monitor for seven days directly following their visit the mobile examination centre.

Return to footnote 6 referrer

Footnote 7

A wide variety of lab tests are done on blood, urine, saliva and hair samples (see Table 3: Laboratory Tests).

Return to footnote 7 referrer

Footnote 8

A limited volume of blood, urine and DNA is stored for future health research.

Return to footnote 8 referrer

Footnote 9

Instructions provided to respondents for providing a second urine sample at home within seven days following their visit to the mobile examination centre.

Return to footnote 9 referrer

Footnote 10

Vision test done on sample of respondents who self-reported being diagnosed with diabetes (type 1 and type 2).

Return to footnote 10 referrer

Footnote 11

Data collected with BpTRU device.

Return to footnote 11 referrer

Footnote 12

Cross-Over study between BpTRU and OMRON with respondents from the second half of cycle 6.

Return to footnote 12 referrer

Footnote 13

Data collected with OMRON device.

Return to footnote 13 referrer

Footnote 14

Data collected with Actical activity monitor, 7 days, when awake.

Return to footnote 14 referrer

Footnote 16

Visual Field and Retinal Photography (FDT & RTP) were not collected for Site 11-16 of Cycle 6.

Return to footnote 16 referrer

Footnote 17

Under review. Might not be part of Cycle 7 and 8.

Return to footnote 17 referrer

Table 3a: Allergies
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Total immunoglobulin E (IgE) B     6-79 6-79    
Table 3b: Laboratory Tests - Bone Health
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013 
Cycle 4
2014-2015 
Cycle 5
2016-2017
Cycle 6
2018-2019 
Age (years)
Procollagen type I N-terminal propeptide B         6-79 6-79
Parathyroid hormone B   3-79     6-79 6-79
C-telopeptide of collagen type I B         6-79
Footnote 1
6-79
Footnote 1
Footnote 1

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 1 referrer

Table 3c: Cardiovascular health
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013 
Cycle 4
2014-2015 
Cycle 5
2016-2017
Cycle 6
2018-2019 
Age (years)
Apolipoprotein A1 (ApoA1) B 6-79 Footnote 1   20-79 Footnote 1 20-79 Footnote 1 20-79 Footnote 1 20-79 Footnote 1
Apolipoprotein B (ApoB) B 6-79
Footnote 1
  20-79 Footnote 1 20-79 Footnote 1 20-79 Footnote 1 20-79 Footnote 1
Fibrinogen B 12-79 12-79        
High density lipoprotein cholesterol (HDL-C) B 6-79 3-79 3-79 3-79 3-79 3-79
High sensitivity C-reactive protein (HsCRP) B 6-79 3-79 3-79 3-79 3-79 3-79
Homocysteine B 6-79       3-79 3-79
Low density lipoprotein cholesterol (LDL-C):
derived variable (Total cholesterol/High density lipoprotein-cholesterol ratio) B   6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1
direct measure B 6-79Footnote 1          
Total cholesterol B 6-79  3-79  3-79  3-79  3-79  3-79 
Triglycerides B 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1
Red blood cell fatty acids:
cis-monosaturated fatty acids: B     20-79 20-79    
cis-vaccenic acid B     20-79 20-79    
oleic acid B     20-79 20-79    
palmitoleic acid B     20-79 20-79    
omega 3 fatty acids: B     20-79 20-79    
alpha-linolenic acid B     20-79 20-79    
docosahexaenoic acid B     20-79 20-79    
n-3 docosapentaenoic acid B     20-79 20-79    
eicosapentaenoic acid B     20-79 20-79    
eicosatetraenoic acid B     20-79 20-79    
omega 6 fatty acids: B     20-79 20-79    
adrenic acid B     20-79 20-79    
arachidonic acid B     20-79 20-79    
dihomo-gamma-linolenic acid B     20-79 20-79    
n-6 docosapentaenoic acid B     20-79 20-79    
gamma-linolenic acid B     20-79 20-79    
linoleic acid B     20-79 20-79    
saturated fatty acids: B     20-79 20-79    
lauric acid B     20-79 20-79    
myristic acid B     20-79 20-79    
palmitic acid B     20-79 20-79    
stearic acid B     20-79 20-79    
trans fatty acids: B     20-79 20-79    
elaidic acid B     20-79 20-79    
palmitelaidic acid B     20-79 20-79    
trans-10 octadecenoic acid B     20-79 20-79    
trans-vaccenic acid B     20-79 20-79    
Red blood cell fatty acid calculated variables:
alpha-Linolenic acid/Eicosapentaenoic acid B     20-79 20-79    
Arachidonic acid/Eicosapentaenoic acid B     20-79 20-79    
Eicosapentaenoic acid/Arachidonic acid B            
Omega-3 index B     20-79 20-79    
Total 18:1 cis fatty acids B     20-79 20-79    
Total cis-monounsaturated fatty acids B     20-79 20-79    
Total n-3 PUFA B     20-79 20-79    
Total n-3 (18:4; 20:4; 20:5; 22:5; 22:6) B     20-79 20-79    
Total n-6 PUFA B     20-79 20-79    
Total n-6 (18:3; 20:3; 20:4; 22:4; 22:5) B     20-79 20-79    
Total n-6 PUFA/Total n-3 PUFA B     20-79 20-79    
Total n-6 LC-PUFA/ Total n-3 LC-PUFA B     20-79 20-79    
Total polyunsaturated fatty acids B     20-79 20-79    
Total saturated fatty acids B     20-79 20-79    
Total 18:1 trans fatty acids B     20-79 20-79    
Total 18:2 trans fatty acids B     20-79 20-79    
Total 18:3 trans fatty acids B     20-79 20-79    
Total trans fatty acids B     20-79 20-79    
Footnote 1

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 1 referrer

Footnote 2

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 2 referrer

Table 3d: Chemistry panel
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Alanine aminotransferase (ALT) B 6-79 3-79   3-79   3-79
Albumin B 6-79 3-79 3-79 3-79 3-79 3-79
Alkaline phosphatase (ALKP) B 6-79 3-79 3-79 3-79 3-79 3-79
Aspartate aminotransferase (AST) B 6-79 3-79 3-79 3-79 3-79 3-79
Bicarbonate (CO2) B 6-79          
Calcium B 6-79 3-79 3-79 3-79 3-79 3-79
Chloride B 6-79 3-79 3-79 3-79 3-79 3-79
Creatinine B 6-79 3-79 3-79 3-79 3-79 3-79
Gamma-glutamyl transferase (GGT) B 6-79 3-79 3-79 3-79 3-79 3-79
Lactate dehydrogenase (LD) B 6-79          
Magnesium B     3-79 3-79 3-79 3-79
Phosphorus B 6-79 3-79 3-79 3-79 3-79 3-79
Potassium B 6-79 3-79 3-79 3-79 3-79 3-79
Sodium B 6-79 3-79 3-79 3-79 3-79 3-79
Total bilirubin (TBIL) B 6-79 3-79        
Total protein (TP) B 6-79 3-79 3-79 3-79 3-79 3-79
Urea B 6-79 3-79 3-79 3-79 3-79 3-79
Uric Acid B 6-79 3-79 3-79 3-79 3-79 3-79
Table 3e: Complete blood count
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Hemoglobin:
hemoglobin B 6-79 3-79 3-79 3-79 3-79 3-79
mean corpuscular hemoglobin B 6-79 3-79 3-79 3-79 3-79 3-79
mean corpuscular hemoglobin concentration B 6-79 3-79 3-79 3-79 3-79 3-79
Platelets:
mean platelet volume B 6-79 3-79        
platelet count B 6-79 3-79 3-79 3-79 3-79 3-79
Red blood cell:
hematocrit B 6-79 3-79 3-79 3-79 3-79 3-79
mean corpuscular volume B 6-79 3-79 3-79 3-79 3-79 3-79
red cell distribution width B 6-79 3-79 3-79 3-79 3-79 3-79
red blood cell count (RBC) B 6-79 3-79 3-79 3-79 3-79 3-79
White blood cell:
basophils B 6-79 3-79        
eosinophils B 6-79 3-79        
lymphocytes B 6-79 3-79        
neutrophils B 6-79 3-79        
monocytes B 6-79 3-79        
white blood cell count (WBC) B 6-79 3-79 3-79 3-79 3-79 3-79
Table 3f: Diabetes
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Glucose - plasma B 6-79          
Glucose - serum B   3-79 6-79Footnote 1 6-79Footnote 1 3-79 3-79
Glycated hemoglobin A1c (HbA1c) B 6-79 6-79 6-79 6-79 6-79 6-79
Insulin B 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1 6-79Footnote 1
Footnote 1

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 1 referrer

Table 3g: Kidney health
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Microalbumin U 6-79 6-79        
Table 3h: Nutritional status
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013 
Cycle 4
2014-2015 
Cycle 5
2016-2017
Cycle 6
2018-2019 
Age (years)
Ferritin B   3-79 3-79 3-79 3-79 3-79
Iodine ((MEC)) U 6-79 3-79 3-79 3-79 3-19 (M), 3-39 (F) 3-19 (M), 3-39 (F)
Iodine (hhld visit) U         3-19 (M), 3-39 (F) 3-19 (M), 3-39 (F)
Iodine/creatinine ratio (hhld & (MEC)) U         3-19 (M), 3-39 (F) 3-19 (M), 3-39 (F)
Sodium (hhld & (MEC)) U         3-79 3-79
Potassium (hhld & (MEC)) U         3-79 3-79
Red blood cell folate B 6-79 3-79 3-79 3-79 3-79 3-79
Vitamin B12 B 6-79 3-79 3-79 3-79 3-79 3-79
Vitamin C (L-ascorbic acid) B     6-79Footnote 1      
Total Vitamin D3 [25-OH] - plasma B 6-79 3-79        
Vitamin D3 [25-OH] - serum B         3-79 3-79
Vitamin D3 [3-epi-25-OH] - serum B         3-79 3-79
Vitamin D2 [25-OH] - serum B         3-79 3-79
Total Vitamin D [25(OH)] - serum B     3-79 3-79 3-79 3-79
  • (F) = Females
  • (M) = Males
Footnote 1

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 1 referrer

Table 3i: Reproductive hormones
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013 
Cycle 4
2014-2015 
Cycle 5
2016-2017
Cycle 6
2018-2019 
Age (years)
Estradiol (E2) B     6-79 6-79    
Follicle-stimulating hormone (FSH) B     6-79Footnote 3 (F) 6-79Footnote 3 (F)    
Luteinizing hormone (LH) B     6-79 (F) 6-79Footnote 3 (F)    
Progesterone (P4) B     6-79Footnote 3 (F) 6-79Footnote 3 (F)    
Testosterone B     6-79Footnote 3 (M) 6-79Footnote 3 (M)    
  • (F) = Females
  • (M) = Males
Footnote 3

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 3 referrer

Table 3j: Thyroid status
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013 
Cycle 4
2014-2015 
Cycle 5
2016-2017
Cycle 6
2018-2019 
Age (years)
anti-thyroglobulin B     3-79 3-79    
anti-thyroid peroxidase B     3-79 3-79    
free thyroxine B     3-79 3-79 3-79 3-79
thyroid stimulating hormone B     3-79 3-79 3-79 3-79
Table 3k: Environmental exposure
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Bisphenol A (BPA) U 6-79 3-79Footnote 2 3-79 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
Ethylene thiourea (ETU) U         3-79Footnote 2 3-79Footnote 2
ortho-phenylphenol (OPP) U            
Ortho-phenylphenol glucuronide (OPP-G) U         3-79Footnote 2 3-79Footnote 2
Ortho-phenylphenol sulphate (OPP-S) U         3-79Footnote 2 3-79Footnote 2
Pooled serum organohalogens B     3-79 (P) 3-79 (P) 3-79 (P) 3-79 (P)
Triclocarban U   3-79Footnote 2        
Triclosan U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
Acrylamide:
acrylamide hemoglobin adduct B     3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
glycidamide hemoglobin adduct B     3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
Benzene metabolites:
tt-muconic acid U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
phenol U   3-79Footnote 2        
s-phenylmercapturic acid U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
Carbamate insecticides:
carbofuranphenol U   3-79Footnote 2        
2-isopropoxyphenol U   3-79Footnote 2        
Chlorophenols:
2,4-dichlorophenol (2,4-DCP) U 6-79 3-79Footnote 2        
2,5-dichlorophenol (2,5-DCP) U   3-79Footnote 2        
pentachlorophenol U   3-79Footnote 2        
2,4,5-trichlorophenol U   3-79Footnote 2        
2,4,6-trichlorophenol U   3-79Footnote 2        
Metals and trace elements:
alumunium H         20-59  
antimony U 6-79 3-79        
antimony H         20-59  
arsenic (speciated):
arsenobetaine/arsenocholine U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
arsenocholine U     3-79Footnote 2 3-79Footnote 2    
arsenic (V) acid U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
arsenous (III) acid U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
dimethylarsinic acid U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
monomethylarsonic acid U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
Inorganic-related arsenic species DV       3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
arsenic (total) B 6-79          
arsenic (total) U 6-79 3-79        
arsenic (total) H         20-59  
barium H         20-59  
beryllium H         20-59  
bismuth H         20-59  
boron U         3-79Footnote 2 3-79Footnote 2
cadmium B 6-79 3-79 3-79 3-79 3-79 3-79
cadmium U 6-79 3-79     3-79Footnote 2 3-79Footnote 2
cadmium H         20-59  
cesium U   3-79        
chromium H         20-59  
cobalt B   3-79        
cobalt U   3-79        
cobalt H         20-59  
copper B 6-79 3-79        
copper U 6-79 3-79        
copper H         20-59  
fluoride U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
lead B 6-79 3-79 3-79 3-79 3-79 3-79
lead U 6-79 3-79        
lead H         20-59  
lithium H         20-59  
manganese B 6-79 3-79        
manganese U 6-79 3-79        
manganese H         20-59  
mercury:
inorganic B 6-79Footnote 2       3-19Footnote 2 3-19Footnote 2
inorganic U 6-79   3-79 3-79    
methyl B     20-79Footnote 2 20-79Footnote 2 3-19Footnote 2 3-19Footnote 2
total B 6-79 3-79 3-79 3-79 3-79 3-79
total H         20-59  
molybdenum B 6-79 3-79        
molybdenum U 6-79 3-79        
molybdenum H         20-59  
nickel B 6-79 3-79        
nickel U 6-79 3-79        
nickel H         20-59  
platinum H         20-59  
red blood cell chromium B         3-79Footnote 2 3-79Footnote 2
selenium B 6-79 3-79     3-79 3-79
selenium U 6-79 3-79        
selenium H         20-59  
silver B   3-79        
silver U   3-79        
silver H         20-59  
tellurium H         20-59  
thallium U   3-79        
thallium H         20-59  
thorium H         20-59  
tungsten U   3-79        
uranium B 6-79 3-79        
uranium U 6-79 3-79        
uranium H            
vanadium U 6-79 3-79        
vanadium H         20-59  
zinc B 6-79 3-79        
zinc U 6-79 3-79        
zinc H 0000       20-59  
Organochlorine pesticides:
aldrin B 20-79Footnote 1Footnote 2          
alpha-chlordane B 20-79Footnote 1Footnote 2          
gamma-chlordane B 20-79Footnote 1Footnote 2          
cis-nonachlor B 20-79Footnote 1Footnote 2          
trans-nonachlor B 20-79Footnote 1Footnote 2          
oxychlordane B 20-79Footnote 1Footnote 2          
beta-hexachlorocyclohexane (ß-HCH) B 20-79Footnote 1Footnote 2          
gamma-hexachlorocyclohexane (γ-HCH) B 20-79Footnote 1Footnote 2          
hexachlorobenzene (HCB) B 20-79Footnote 1Footnote 2          
mirex B 20-79Footnote 1Footnote 2          
p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) B 20-79Footnote 1Footnote 2          
p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT) B 20-79Footnote 1Footnote 2          
Toxaphene parlar 26 B 20-79Footnote 1Footnote 2          
Toxaphene parlar 50 B 20-79Footnote 1Footnote 2          
Organophosphate insecticides
acephate U     3-79Footnote 2Footnote 5      
dimethylphosphate (DMP) U 6-79Footnote 2 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
dimethylthiophosphate (DMTP) U 6-79Footnote 2 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
dimethyldithiophosphate (DMDTP) U 6-79Footnote 2 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
diethylphosphate (DEP) U 6-79Footnote 2 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
diethylthiophosphate (DETP) U 6-79Footnote 2 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
diethyldithiophosphate (DEDTP) U 6-79Footnote 2 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
malathion dicarboxylic acid U     3-79Footnote 2Footnote 5 3-79Footnote 2    
methamidophos U     3-79Footnote 2Footnote 5      
3,5,6 trichloro-2-pyridinol U     3-79Footnote 2Footnote 5 3-79Footnote 2    
Parabens:
butyl paraben U     3-79Footnote 2Footnote 5 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
ethyl paraben U     3-79Footnote 2Footnote 5 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
methylparaben U     3-79Footnote 2Footnote 5 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
propyl paraben U     3-79Footnote 2Footnote 5 3-79Footnote 2 3-79Footnote 2 3-79Footnote 2
Iso-butylparaben U            
Perfluoroakyl substances:
perfluorobutane sulfonate (PFBS) B   12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluorodecanoic acid (PFDA) B   12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluorohexane sulfonate (PFHxS) B 20-79 12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluorohexanoic acid (PFHxA) B   12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluoro-n-butyric acid (PFBA) B   12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluorononanoic acid (PFNA) B   12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluorooctane sulfonate (PFOS) B 20-79 12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluorooctanoic acid (PFOA) B 20-79 12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
perfluoroundecanoic acid (PFUDA) B   12-79Footnote 2     3-79Footnote 2 3-79Footnote 2
Phenoxy Herbicide:
2,4-dichlorophenoxyacetic acid (2,4-D) U 6-79 3-79Footnote 2        
Phthalate metabolites:
mono benzyl phthalate (MBzP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-3-carboxypropyl phthalate (MCPP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-3-hydroxy-n-butyl phthalate (3OH-MBP) U         3-79Footnote 2 3-79Footnote 2
mono cyclohexyl phthalate (MCHP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-2-ethylhexyl phthalate (MEHP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono ethyl phthalate (MEP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-iso-butyl phthalate (MiBP) U   3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-isononyl phthalate (MiNP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-n-butyl phthalate (MnBP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-n-octyl phthalate (MOP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-methyl phthalate (MMP) U 6-49 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
mono-carboxy-n-heptyl phthalate (MCHpP) U         3-79Footnote 2 3-79Footnote 2
mono-(2-ethyl-5-carboxypentyl) phthalate (MECPP) U         3-79Footnote 2 3-79Footnote 2
mono-(2-carboxymethylhexyl) phthalate (MCMHP) U         3-79Footnote 2 3-79Footnote 2
mono-(carboxyisooctyl) phthalate (MCIOP) U         3-79Footnote 2 3-79Footnote 2
mono-(oxoisononyl) phthalate (MOINP) U         3-79Footnote 2 3-79Footnote 2
mono-(hydroxyisononyl) phthalate (MHINP) U         3-79Footnote 2 3-79Footnote 2
monocarboxyisononyl phthalate (MCiNP) U         3-79Footnote 2 3-79Footnote 2
mono-isodecyl phthalate (MIDP) U         3-79Footnote 2 3-79Footnote 2
monooxoisodecyl phthalate (MOiDP) U         3-79Footnote 2 3-79Footnote 2
monohydroxyisodecyl phthalate (MHiDP) U         3-79Footnote 2 3-79Footnote 2
Polyaromatic hydrocarbons:
chrysenes:
2-hydroxychrysene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
3-hydroxychrysene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
4-hydroxychrysene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
6-hydroxychrysene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
fluoranthene:
3-hydroxyfluoranthene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
fluorenes:
2-hydroxyfluorene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
3-hydroxyfluorene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
9-hydroxyfluorene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
napthalenes:
1-hydroxynaphthol U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
2-hydroxynaphthol U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
phenanthrenes:
1-hydroxyphenanthrene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
2-hydroxyphenanthrene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
3-hydroxyphenanthrene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
4-hydroxyphenanthrene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
9-hydroxyphenanthrene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
pyrene:
3-hydroxybenzo(a)pyrène U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
1-hydroxypyrene U   3-79Footnote 2 3-79Footnote 2 3-79Footnote 2    
Alternate plasticizers
mono-isononyl-cyclohexane-1,2-dicarboxylate (MINCH) U         3-79Footnote 2 3-79Footnote 2
1,2-(trans-cyclohexane-dicarboxylate)-mono-(7-carboxylate-4-methyl) heptyl ester (trans-cx-MINCH) U         3-79Footnote 2 3-79Footnote 2
1,2-(cis-cyclohexane-dicarboxylate)-mono-(7-carboxylate-4-methyl) heptyl ester (cis-cx-MINCH) U         3-79Footnote 2 3-79Footnote 2
cis-cyclohexane-1,2-dicarboxylic acid (cis-CHDA) U         3-79Footnote 2 3-79Footnote 2
1,2-(cyclohexane-dicarboxylate)-mono-(7-hydroxy-4-methyl) octyl ester (OH-MINCH) U         3-79Footnote 2 3-79Footnote 2
1,2-(cyclohexane-dicarboxylate)-mono-(7-oxo-4-methyl) octyl ester (oxo-MINCH) U         3-79Footnote 2 3-79Footnote 2
1,2-(trans-cyclohexane-dicarboxylate)-mono-4-methyloctyl ester (trans-MINCH) U         3-79Footnote 2 3-79Footnote 2
2,2,4-trimethyl-1,2-pentanediol (TMPD) U         3-79Footnote 2 3-79Footnote 2
2,2,4-trimethyl-3-hydroxy valeric acid (HTMV) U         3-79Footnote 2 3-79Footnote 2
1,2,4-benzenetricarboxylate 1-(2-ethylhexyl) ester (1-MEHTM) U         3-79Footnote 2 3-79Footnote 2
1,2,4-benzenetricarboxylate 2-(2-ethylhexyl) ester (2-MEHTM) U         3-79Footnote 2 3-79Footnote 2
1,2,4-benzenetricarboxylate 4-(2-ethylhexyl) ester (4-MEHTM) U         3-79Footnote 2 3-79Footnote 2
Polybrominated flame retardants:
Polybrominated biphenyls 153 (PBB 153) B 20-79Footnote 1Footnote 2          
Polybrominated diphenyl ether (PBDE) 15, 17,  B 20-79Footnote 1Footnote 2          
PBDE 25, 28, 33, 47, 99, 100, 153 B 20-79Footnote 1Footnote 2          
Polychlorinated biphenyls (PCBs):
Aroclor 1260 B 20-79Footnote 1Footnote 2          
PCB 28, 52, 66, 74, 99, 101, 105, 118, B 20-79Footnote 1Footnote 2          
PCB 128, 138, 146, 153, 156, 163, 167, 170, B 20-79Footnote 1Footnote 2          
PCB 178, 180, 183, 187, 194, 201, 203, 206 B 20-79Footnote 1Footnote 2          
Pyrethroids pesticides:
cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylic acid (cis-DBCA) U 6-79 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid (cis-DCCA) U 6-79 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
4-fluoro-3-phenoxybenzoic acid (4-F-3-PBA) U 6-79 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
3-phenoxybenzoic acid (3-PBA) U 6-79 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid (trans-DCCA) U 6-79 3-79Footnote 2     3-79Footnote 2 3-79Footnote 2
Tobacco:
nicotine and metabolites:
anabasine U 12-79Footnote 2   12-79   12-79  
free cotinine U 6-79 3-79 3-79 3-79 3-79 6-79Footnote 2
free cotinine S           6-79
total cotinine U 12-79Footnote 2          
cotinine-n-glucuronide U 12-79Footnote 2   12-79   12-79  
nicotine U 12-79Footnote 2   12-79   12-79  
nicotine-n-glucuronide U 12-79Footnote 2   12-79   12-79  
trans-3-hydroxycotinine free U 12-79Footnote 2   12-79   12-79 12-79Footnote 2
trans-3-hydroxycotinine-O-glucuronide U 12-79Footnote 2   12-79   12-79  
NNK metabolites (4-(methyl-nitrosamino)-1-butanone):
free NNAL U 12-79Footnote 2   12-79Footnote 2   12-79Footnote 2  
total NNAL U 12-79Footnote 2   12-79Footnote 2   12-79Footnote 2 6-79Footnote 2
Triazine herbicides:
atrazine mercapturate  U   3-79Footnote 2        
desethylatrazine  U   3-79Footnote 2        
diaminochlorotriazine U   3-79Footnote 2        
Volatile organic compounds:
common fuel pollutants (BTEX):
benzene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
ethylbenzene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
m- & p-xylenes B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
o-xylene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
toluene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
trihalomethanes:
bromodichloromethane B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
dibromochloromethane B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
tribromomethane B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
trichloromethane B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
   halogenated solvents:
carbon tetrachloride B         12-79Footnote 2  
trichloroethylene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
tetrachloroethylene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
1,1,1,2-tetrachloroethane B         12-79Footnote 2  
benzenes:
Isopropylbenzene B         12-79Footnote 2  
Nitrobenzene B         12-79Footnote 2  
1,4-dichlorobenzene B         12-79Footnote 2  
   other:
4-Methyl-2-pentanone B         12-79Footnote 2  
styrene B     12-79Footnote 2 12-79Footnote 2 12-79Footnote 2  
furans:
Tetrahydrofuran B         12-79  
2,5-dimethylfuran B         12-79  
Bisphenol analogues
Bisphenol AF U            
Bisphenol S U            
Bisphenol F U            
Bisphenol B U            
Bisphenol E U            
Bisphenol Z U            
Bisphenol 4-4' (BP4) U            
Flame retardants: BDEs
2-Ethyl-1-hexyl 2,3,4,5-tetrabromobenzoate (EHTBB) or (TBB) B            
bis(2-ethylhexyl) tetrabromophthalate (TBPH) B            
pentabromoethylbenzene (PBEB) B            
5-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (5-OH-BDE-47) B            
6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) B            
6-methoxy-2,2',4,4'-tetrabromodiphenyl ether  (6-MeO-BDE-47) B            
4'-hydroxy-2,2',4,5'- tetrabromodiphenyl ether (4'-OH-BDE-49) B            
2,2',4,4'-Tetrabromodiphenyl ether (PBDE 47) B            
2,2',4,4',5-Pentabromodiphenyl ether (PBDE 99) B            
2,2',4,4',6-Pentabromodiphenyl ether (PBDE 100) B            
2,2',4,4',5,5'-Hexabromodiphenyl ether (PBDE 153) B            
Short-chained chlorinated paraffins (SCCPs) B            
Total short chain (C10-C13) B            
Congener C10H18Cl4 B            
Congener C10H17Cl5 B            
Congener C10H16Cl6 B            
Congener C10H15Cl7 B            
Congener C10H14Cl8 B            
Congener C10H13Cl9 B            
Congener C11H20Cl4 B            
Congener C11H18Cl6 B            
Congener C11H16C8 B            
Congener C12H20Cl6 B            
Congener C12H18C8 B            
Congener C13H24Cl4 B            
Congener C13H22Cl6 B            
Congener C13H20Cl8 B            
Total medium chain (C14-C17) B            
Congener C14H22Cl8 B            
Congener C15H22Cl6 B            
Congener C16H26Cl8 B            
Congener C17H28Cl8 B            
Flame retardants: OP
Bis-2(butoxyethyl) phosphate (BBOEP) U            
Bis(2-chloropropyl) phosphate (BCIPP) U            
Bis(1,3-dichloro-2-propyl)
phosphate (BDCIPP)
U            
Diphenyl phosphate (DPHP) U            
Di-o-cresyl phosphate or Di-o-tolyl phosphate (DoCP) U            
Di-p-cresyl phosphate or Di-p-tolyl-phosphate (DpCP) U            
Food additives
3,5-di-tert-butyl-4-hydroxybenzoic acid (BHT-acid) U            
Polycyclic musks
7-Acetyl-1,1,3,4,4,6-hexamethyltetrahydronaphthalene
[1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)ethanone] (AHTN, Tonalide)
B            
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (HHCB, Galaxolide) B            
UV-related compounds
2,4-dihydroxybenzophenone (Benzophenone-1) U            
2,2',4,4'-tetrahydroxybenzophenone (Benzophenone-2) U            
2-hydroxy-4-methoxybenzophenone (Benzophenone-3) U            
2,2'-dihydroxy-4-methoxybenzophenone (Benzophenone-8) U            
4-hydroxybenzophnenone (4-OH-Benzophenone) U            
2-Ethyl-hexyl-4-methoxycinnamate (Octinoxate; Octylmethoxycinnamate) U            
3-(4-methylbenzylidene)-camphor (enzacamene; 4-MBC) U            
N,N-dimethyl-p-aminobenzoic acid (DMP) U            
N-monomethyl-p-aminobenzoic acid (MMP) U            
Pesticides: DEET and IMPY
N,N-Diethyl-m-toluamide (DEET) U            
m-[(N,N-diethylamino)carbonyl] benzoic acid (DCBA) U            
N,N-Diethyl-m-hydroxymethylbenzamide (DHMB) U            
2-isopropyl-4-methyl-6-hydroxypyrimidine (IMPY) U            
Pesticides: Glyphosate and Glufosinate
Glyphosate (GLYPH) U            
Aminomethylphosphonic acid (AMPA) U            
Glufosinate (GLUF) (or glufosinate ammonium) U            
3-Methylphosphinico propionicacid(3-MPPA) U            
Pesticides: Neonicotinoids
5-Hydroxyimidacloprid U            
N-Desmethylacetamiprid U            
Acetamiprid (NXL) U            
Clothianidin (CTH) U            
Dinotefuran (DTQ) U            
Imidacloprid (ICP) U            
Nitenpyram (NTM) U            
Thiacloprid (TAP) U            
Thiamethoxam (THM) U            

(P) = Pooled Serum

Footnote 1

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 1 referrer

Footnote 2

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 2 referrer

Footnote 5

Data not released due to lab quality issues.

Return to footnote 5 referrer

Table 3l: General characterization
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Specific gravity U   3-79 3-79 3-79 3-79 3-79
Creatinine (hhld & (MEC)) U 6-79 3-79 3-79 3-79 3-79 3-79
Table 3m: Infection markers
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Hepatitis A virus antibody B 14-79          
Hepatitis B surface antigen B 14-79 14-79 14-79 14-79    
Hepatitis B virus surface antibody B 14-79 14-79 14-79      
Hepatitis B virus surface antigen B 14-79 14-79 14-79 14-79    
Hepatitis C virus antibody B 14-79 14-79 14-79 14-79    
Hepatitis C RNA B     14-79Footnote 4 14-79Footnote 4    
Chlamydia trachomatis U   14-59     14-59 14-59
Herpes simplex-2 B   14-59        
Human Papillomavirus U   14-59        
Anti-Toxoplasmosis B         3-79  
Footnote 4

Lab test done on the fasted subgroup of the age range indicated.

Return to footnote 4 referrer

Table 3n: Environmental exposure (IAS, Tested at the household level)
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Acetone IAS   3-79 3-79 3-79    
a-Pinene IAS   3-79 3-79 3-79    
Benzaldehyde IAS   3-79 3-79 3-79    
Benzene IAS   3-79 3-79 3-79    
Benzenepropanol IAS   3-79        
Benzofuran IAS     3-79 3-79    
Biphenyl IAS   3-79        
1-Bromodecane IAS     3-79 3-79    
Bromodichloromethane IAS   3-79 3-79 3-79    
Tribromomethane IAS   3-79 3-79 3-79    
1-Bromooctane IAS     3-79 3-79    
1-Bromopropane IAS     3-79 3-79    
1-Butanol IAS   3-79 3-79 3-79    
2-Butanone IAS   3-79 3-79 3-79    
2-Butoxyethanol IAS   3-79 3-79 3-79    
Butyl ester benzoic acid IAS   3-79        
Camphene IAS   3-79 3-79 3-79    
Carbon tetrachloride IAS   3-79        
Chlorobenzene IAS     3-79 3-79    
1-Chlorododecane IAS     3-79 3-79    
Trichloromethane IAS   3-79 3-79 3-79    
Chloromethylbenzene IAS   3-79 3-79 3-79    
4-Chloro,3-methylphenol IAS   3-79        
3-Chloropropene IAS   3-79        
Cyclohexane IAS   3-79 3-79 3-79    
Cyclohexanol IAS   3-79 3-79 3-79    
Cyclohexanone IAS   3-79 3-79 3-79    
Decamethylcyclopentasiloxane IAS   3-79 3-79 3-79    
Decamethyltetrasiloxane IAS     3-79 3-79    
Decanal IAS   3-79 3-79 3-79    
Decane IAS   3-79 3-79 3-79    
Dibromochloromethane IAS   3-79 3-79 3-79    
1,2-Dibromoethane IAS   3-79 3-79 3-79    
1,2-Dichlorobenzene IAS   3-79 3-79 3-79    
1,4-Dichlorobenzene IAS   3-79 3-79 3-79    
1,1-Dichloroethane IAS     3-79 3-79    
1,2-Dichloroethane IAS     3-79 3-79    
2,4-/2,5-dichlorotoluene IAS   3-79        
1,3-Dichloro-2-propanol IAS     3-79 3-79    
1,2-dichloropropane IAS   3-79        
2,3-dichloropropene IAS   3-79        
1,2-Dimethoxyethane IAS     3-79 3-79    
Dimethoxymethane IAS   3-79        
1,2-Dimethoxy-4-(2-propenyl)benzene IAS   3-79        
Dimethyl ester pentanedioc acid IAS     3-79 3-79    
2,5-Dimethylfuran IAS     3-79 3-79    
1,4-Dioxane IAS   3-79 3-79 3-79    
Dodecamethylcyclohexasiloxane IAS   3-79        
Dodecamethylpentasiloxane IAS     3-79 3-79    
Dodecane IAS   3-79 3-79 3-79    
Ethanediol diacetate IAS   3-79        
1-Ethenylpyrrolidinone IAS   3-79        
2-(2-Ethoxyethoxy)ethanol IAS   3-79        
2-Ethoxyethyl acetate IAS   3-79        
Ethylbenzene IAS   3-79 3-79 3-79    
Ethyl ester benzoic acid IAS   3-79        
2-Ethyl-1-hexanol IAS   3-79 3-79 3-79        
2-Furancarboxaldehyde IAS   3-79 3-79 3-79    
Heptanal IAS     3-79 3-79    
Heptane IAS   3-79 3-79 3-79    
1,1,2,3,4,4-Hexachloro-1,3-butadiene IAS     3-79 3-79    
Hexachloroethane IAS   3-79 3-79 3-79    
Hexamethyldisiloxane IAS     3-79 3-79    
Hexanal IAS   3-79 3-79 3-79    
Hexane IAS   3-79 3-79 3-79    
2-Hexanone IAS     3-79 3-79    
Limonene IAS   3-79 3-79 3-79    
2-Methoxyethyl acetate IAS   3-79        
2-(2-Methoxyethoxy)ethanol IAS   3-79        
2-Methyl-1,3-butadiene IAS   3-79 3-79 3-79    
Methyl ester benzoic acid IAS   3-79        
Methyl ester hexanoic acid IAS   3-79        
1-Methylethylbenzene IAS   3-79 3-79 3-79    
5-Methyl-2-hexanone IAS   3-79 3-79 3-79    
4-Methyl-2-pentanone IAS   3-79 3-79 3-79    
4-Methylpenten-2-one IAS   3-79        
2-Methyl-2-propanol IAS   3-79 3-79 3-79    
2-Methylpropyl ester benzoic acid IAS   3-79        
1-Methylpyrrolidinone IAS   3-79        
Naphthalene IAS   3-79 3-79 3-79    
Nitromethane IAS   3-79        
1-Nitropropane IAS   3-79        
2-Nitropropane IAS   3-79        
2-nitrotoluene IAS   3-79        
Nonanal IAS   3-79 3-79 3-79    
Nonane IAS     3-79 3-79    
Nonanol IAS   3-79        
Octamethylcyclotetrasiloxane IAS   3-79 3-79 3-79    
Octamethyltrisiloxane IAS     3-79 3-79    
Octanal IAS   3-79 3-79 3-79    
Octane IAS     3-79 3-79    
Octanol IAS   3-79        
Pentachloroethane IAS     3-79 3-79    
Pentane IAS   3-79 3-79 3-79    
1-Pentanol IAS   3-79 3-79 3-79    
Pentanone IAS   3-79        
2-Pentanone IAS     3-79 3-79    
Perchloroethylene IAS   3-79 3-79 3-79    
Phenol IAS     3-79 3-79    
1-Propanol IAS   3-79        
2-Propanol IAS   3-79 3-79 3-79    
Quinoline IAS   3-79 3-79 3-79    
Styrene IAS   3-79 3-79 3-79    
1,1,1,2-Tetrachloroethane IAS     3-79 3-79    
Tetrahydrofuran IAS   3-79 3-79 3-79    
Toluene IAS   3-79 3-79 3-79    
1,2,3-Trichlorobenzene IAS     3-79 3-79    
1,2,4-Trichlorobenzene IAS     3-79 3-79    
1,3,5-Trichlorobenzene IAS     3-79 3-79    
1,1,2-Trichloroethane IAS     3-79 3-79    
Trichloroethylene IAS   3-79        
1,2,3-Trichloropropane IAS     3-79 3-79    
1,2,3-Trimethylbenzene IAS   3-79 3-79 3-79    
1,2,4-trimethylbenzene IAS   3-79 3-79 3-79    
1,3,5-Trimethylbenzene IAS     3-79 3-79    
3,5,5-Trimethyl-2-cyclohexen-1-one IAS   3-79        
Undecane IAS   3-79 3-79 3-79    
o-Xylene IAS   3-79 3-79 3-79    
m,p-Xylene IAS   3-79 3-79 3-79    
Table 3o: Environmental exposure (household tap water subsample)
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
Fluoride TWS     3-79 3-79    
Volatile organic compounds
Common fuel pollutants (BTEX)
Benzene TWS     3-79 3-79    
Ethylbenzene TWS     3-79 3-79    
m- & p-Xylenes TWS     3-79 3-79    
o-Xylene TWS     3-79 3-79    
Toluene TWS     3-79 3-79    
Total xylene TWS     3-79 3-79    
Trihalomethanes
Bromodichloromethane TWS     3-79 3-79    
Dibromochloromethane TWS     3-79 3-79    
Tribromomethane TWS     3-79 3-79    
      Trichloromethane TWS     3-79 3-79    
Metals and trace elements in water              
Antimony (Sb) TWS            
Arsenic (total) (As) TWS            
Beryllium (Be) TWS            
Boron (Bo) TWS            
Cadmium (Cd) TWS            
Chromium (Cr) TWS            
Cobalt (Co) TWS            
Copper (Cu) TWS            
Lead (Pb) TWS            
Manganese (Mn) TWS            
Molybdenum (Mo) TWS            
Nickel (Ni) TWS            
Selenium (Se) TWS            
Silver (Ag) TWS            
Uranium (Ur) TWS            
Zinc (Zn) TWS            
Table 4: BiobankFootnote 1
Subject Matrix Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
2014-2015
Cycle 5
2016-2017
Cycle 6
2018-2019
Age (years)
DNA Storage B/S 20-79 20-79 14-79 14-79 3-79 3-79
Buffy Coat Storage Buf            
Urine Storage U 6-79 3-79 3-79 3-79 3-79 3-79
Plasma Storage B 6-79 3-79 3-79 3-79 3-79 3-79
Whole Blood Storage B 6-79 3-79 3-79 3-79 3-79 3-79
Serum Storage B 6-79 3-79 3-79 3-79 3-79 3-79
Footnote 1

Limited quantities, availability may vary.

Buffy coat will be stored starting in Cycle 7 instead of DNA extraction.

Return to footnote 1 referrer